We offer 2D soft matrices that are fully compatible with existing industrial processes and meet industry quality requirements for cell culture. Our soft culture plates display mechanical features close to those found in vivo in animal or human tissues. They are flat hydrogels that exhibit either uniform (with physiological rigidities of 0.5 to 100kPa) or patterned mechanical properties (with, for the first time, gradients of rigidity from Pa/mm to kPa/μm) as seen in vivo. Additionally, the plates are pre-coated with adhesion proteins and guarantee the reproducibility of the chemical environment. Overall, our soft culture plates provide a ready-to-use, 2D model of the biomechanical cell environment for cell-based assays.
Our soft plates are compatible with robots, standard downstream cell analysis, and standard imaging techniques including inverted microscopy.
Customers can test non-uniform mechanical properties based on customizable standard patterns (steps of rigidities, stripes that mimic fibers, geometrical shapes) and can choose the chemical coating from 4 proteins of the extracellular matrix (fibronectin, vitronectin, laminine, collagen I) and the amino acids chains poly-lysine or poly-ornithine.
With the use of patented and innovative technologies, these new culture plates aim to induce the emergence of physiologically relevant cell phenotypes and responses, and are thus targeted at cancer research, stem cell differentiation, drug discovery, the cells and proteins markets, cosmetics, and other applications.